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Lugdunin

CAT: 0804-HY-P4200-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P4200-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1989698-37-4
UNSPSC Description
Lugdunin is an antibiotic peptide. Lugdunin inhibits bacteria by dissipating their membrane potential. Lugdunin is active against Gram-positive bacteria, such as S. aureus, and reduces S. aureus skin and nasal colonization. Lugdunin induces LL-37 and CXCL8/MIP-2 in human keratinocytes and mouse skin[1].
Target Antigen
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lugdunin.html
Purity
95.44
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C1([H])N[C@](CS1)([H])C(N[C@@H](C(N2)=O)C(C)C)=O)C(C)C)=O)C(C)C)=O)C(C)C)=O)CC(C)C)[C@@H]2CC3=CNC4=CC=CC=C34
Molecular Weight
783.04
References & Citations
[1]Bitschar K, et al. Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors. Nat Commun. 2019 Jun 21;10(1):2730.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Clinical Information
No Development Reported

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CatalogName
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