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TOP5668

CAT: 0804-HY-160857-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160857-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TOP5668 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5668 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats[1].
CAS Number
1850256-71-1
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/top5668.html
Purity
98.07
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(OC)=NC(C2=CC3=C(C=C2OC)OCC4=C3N(C5=CC(Cl)=CC(Cl)=C5)N=C4C(N(C(C)(C)C)C)=O)=C1)N
Molecular Formula
C30H29Cl2N5O5
Molecular Weight
610.49
References & Citations
[1]Nataraja S, et al. Discovery and Preclinical Development of Orally Active Small Molecules that Exhibit Highly Selective Follicle Stimulating Hormone Receptor Agonism. Front Pharmacol. 2021 Jan 14;11:602593.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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