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Demethylregelin

CAT: 0804-HY-N1695Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N1695Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Demethylregelin (Regelin acid), a triterpene, effectively reduces the expression of iNOS protein and subsequent nitric oxide production induced by lipopolysaccharide in RAW264.7 cells. Demethylregelin has anti-inflammatory activities[1].
CAS Number
173991-81-6
Product Name Alternative
Regelin acid
UNSPSC
12352211
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/demethylregelin.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C(CC[C@]2(C)[C@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C(O)=O)C[C@H](O)[C@@](C)5CC[C@](C)4[C@@](C)3CC[C@@]12C)=O
Molecular Formula
C31H48O4
Molecular Weight
484.71
References & Citations
[1]Eun Ju Jeong, et al. Anti-inflammatory Triterpenes from Euonymus alatus Leaves and Twigs on Lipopolysaccharide-activated RAW264.7 Macrophage Cells. Bull. Korean Chem. Soc. 2014, Vol. 35, No. 10 2945|[2]Eun Ju Jeong, et al. ChemInform Abstract: Antiinflammatory Triterpenes from Euonymus alatus Leaves and Twigs on Lipopolysaccharide-Activated RAW264.7 Macrophage Cells. March 2015ChemInform 46.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported