Fatty Acid Desaturase 2 Human Recombinant

• Description:

  Fatty Acid Desaturase 2 Human Recombinant_x000D_ Catalog number: B2018716_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 300 µg_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: ˆ’20°C_x000D_ Keywords: Acyl-CoA (8-3)-Desaturase, FADS1, Δ5 Fatty Acid Desaturase_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Leone P, Quarta S, Tolomeo M, Barile M. Purification of Recombinant Human 6His-FAD Synthase (Isoform 2) and Quantitation of FAD/Protein Monomer Ratio by UV-Vis Spectra Methods Mol Biol. 2021;2280:69-85._x000D_ 2: Leone P, Galluccio M, Brizio C, Barbiroli A, Iametti S, Indiveri C, Barile M. The hidden side of the human FAD synthase 2 Int J Biol Macromol. 2019 Oct 1;138:986-995._x000D_ 3: Galluccio M, Indiveri C. Heterologous Overexpression of Human FAD Synthase Isoforms 1 and 2 Methods Mol Biol. 2021;2280:55-67._x000D_ 4: Schübel R, Jaudszus A, Krüger R, Roth A, Klempt M, Barth SW. Dietary essential α-linolenic acid and linoleic acid differentially modulate TNFα-induced NFκB activity in FADS2-deficient HEK-293 cells Int J Food Sci Nutr. 2017 Aug;68(5):553-559._x000D_ 5: Torchetti EM, Bonomi F, Galluccio M, Gianazza E, Giancaspero TA, Iametti S, Indiveri C, Barile M. Human FAD synthase (isoform 2): a component of the machinery that delivers FAD to apo-flavoproteins FEBS J. 2011 Nov;278(22):4434-49._x000D_ 6: Park WJ, Kothapalli KS, Lawrence P, Brenna JT. FADS2 function loss at the cancer hotspot 11q13 locus diverts lipid signaling precursor synthesis to unusual eicosanoid fatty acids PLoS One. 2011;6(11):e28186._x000D_ 7: Wang GJ, Tian Y, Zhang HY. [Research Progress of Fatty Acid Desaturase 2 Gene in Glycolipid Metabolism] Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2022 Feb;44(1):158-163._x000D_ 8: Vila IK, Chamma H, Steer A, Saccas M, Taffoni C, Turtoi E, Reinert LS, Hussain S, Marines J, Jin L, Bonnefont X, Hubert M, Schwartz O, Paludan SR, Van Simaeys G, Doumont G, Sobhian B, Vlachakis D, Turtoi A, Laguette N. STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses Cell Metab. 2022 Jan 4;34(1):125-139.e8._x000D_ 9: Yamane D, Hayashi Y, Matsumoto M, Nakanishi H, Imagawa H, Kohara M, Lemon SM, Ichi I. FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication Cell Chem Biol. 2022 May 19;29(5):799-810.e4._x000D_ 10: Shockey J, Gilbert MK, Thyssen GN. A mutant cotton fatty acid desaturase 2-1d allele causes protein mistargeting and altered seed oil composition BMC Plant Biol. 2023 Mar 17;23(1):147. _x000D_ _x000D_ Products Related to Fatty Acid Desaturase 2 Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2018716 (300 µg)_x000D_ Fatty Acid Desaturase 2 (FADS2) is an enzyme that plays a key role in the biosynthesis of long-chain polyunsaturated fatty acids (PUFAs) in humans. It is involved in the desaturation of fatty acids, converting saturated and monounsaturated fatty acids into polyunsaturated fatty acids, such as omega-3 and omega-6 fatty acids. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3