ARC186

• UNSPSC Description:

  ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to HY-147080 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.

• Target Antigen:

  Complement System

• Type:

  Oligonucleotides

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/non-pegylated-naked-arc186.html

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  [fCmGfCfCGfCmGmGfUfCfUfCmAmGmGfCGfCfUmGmAmGfUfCfUmGmAmGfUfUfUAfCfCfUmGfCmG-3T]

• Molecular Weight:

  12702.76

• References & Citations:

  [1]Aptamer therapeutics useful in the treatment of complement-related disorders. WO2006088888A2.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported