Nor-NOHA

• Description:

  nor-NOHA _x000D_ Catalog number: B2019453_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 mg_x000D_ Molecular Weight or Concentration: 296.3_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: RT_x000D_ Keywords: 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate Nω-hydroxy-nor-Arginine_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Ng KP, Manjeri A, Lee LM, Chan ZE, Tan CY, Tan QD, Majeed A, Lee KL, Chuah C, Suda T, Ong ST. The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target PLoS One. 2018 Oct 11;13(10):e0205254._x000D_ 2: Chauhan S, Nusbaum RJ, Huante MB, Holloway AJ, Endsley MA, Gelman BB, Lisinicchia JG, Endsley JJ. Therapeutic Modulation of Arginase with nor-NOHA Alters Immune Responses in Experimental Mouse Models of Pulmonary Tuberculosis including in the Setting of Human Immunodeficiency Virus (HIV) Co-Infection Trop Med Infect Dis. 2024 Jun 6;9(6):129._x000D_ 3: Reid KM, Tsung A, Kaizu T, Jeyabalan G, Ikeda A, Shao L, Wu G, Murase N, Geller DA. Liver I/R injury is improved by the arginase inhibitor, N(omega)-hydroxy-nor-L-arginine (nor-NOHA) Am J Physiol Gastrointest Liver Physiol. 2007 Feb;292(2):G512-7._x000D_ 4: Xiong M, Chen H, Fan Y, Jin M, Yang D, Chen Y, Zhang Y, Petersen RB, Su H, Peng A, Wang C, Zheng L, Huang K. Tubular Elabela-APJ axis attenuates ischemia-reperfusion induced acute kidney injury and the following AKI-CKD transition by protecting renal microcirculation Theranostics. 2023 Jun 4;13(10):3387-3401._x000D_ 5: Bagnost T, Guillaume YC, Thomassin M, Berthelot A, Demougeot C, André C. Biochromatographic framework for analyzing magnesium chloride salt dependence on nor-NOHA binding to arginase enzyme J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 15;873(1):37-40._x000D_ 6: Li X, Zhu F, He Y, Luo F. [Arginase inhibitor nor-NOHA induces apoptosis and inhibits invasion and migration of HepG2 cells] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Apr;33(4):477-482._x000D_ 7: Bagnost T, Guillaume YC, Thomassin M, Robert JF, Berthelot A, Xicluna A, André C. Immobilization of arginase and its application in an enzymatic chromatographic column: thermodynamic studies of nor-NOHA/arginase binding and role of the reactive histidine residue J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):113-20._x000D_ 8: Ding LY, Chen LM, Wang MZ, Zhang J, Loor JJ, Zhou G, Zhang X, Wang HR. Inhibition of arginase via jugular infusion of N(ω)-hydroxy-nor-l-arginine inhibits casein synthesis in lactating dairy cows J Dairy Sci. 2018 Apr;101(4):3514-3523._x000D_ 9: Abdelkawy KS, Lack K, Elbarbry F. Pharmacokinetics and Pharmacodynamics of Promising Arginase Inhibitors Eur J Drug Metab Pharmacokinet. 2017 Jun;42(3):355-370._x000D_ 10: Momma TY, Ottaviani JI. Arginase inhibitor, N(ω)-hydroxy-L-norarginine, spontaneously releases biologically active NO-like molecule: Limitations for research applications Free Radic Biol Med. 2020 May 20;152:74-82. _x000D_ _x000D_ Products Related to nor-NOHA can be found at Chemicals

• Short Description:

  Catalog Number: B2019453 (1 mg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5