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Picraline

CAT: 0804-HY-N3072Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N3072Size:1 Each
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Description
Picraline is a natural alkaloid that targets opioid receptors with binding affinities with Ki values of 132 μM, 2.38 μM and 98.8 μM for μOR, κOR and δOR, respectively[1].
CAS Number
2671-32-1
UNSPSC
12352005
Target
Opioid Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/picraline.html
Solubility
10 mM in DMSO
Smiles
CC(OC[C@]([C@]1(C2=CC=CC=C2N3)[C@@]3(O4)[C@@]5([H])N(C/6)[C@]4([H])C1)([C@@](C6=C/C)([H])C5)C(OC)=O)=O
Molecular Formula
C23H26N2O5
Molecular Weight
410.46
References & Citations
[1]Simone M Creed, et al. Isolation and Pharmacological Characterization of Six Opioidergic Picralima nitida Alkaloids. J Nat Prod. 2021 Jan 22;84 (1) :71-80.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
δ Opioid Receptor/DOR; κ Opioid Receptor/KOR; μ Opioid Receptor/MOR

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