Octachlorodibenzo-p-dioxin

• UNSPSC Description:

  Octachlorodibenzo-p-dioxin (OCDD) is an environmental contaminant but is not acutely toxic. In rats, Octachlorodibenzo-p-dioxin (50 μg/kg i.v. or 50-5000 μg/kg p.o.) has a systemic elimination half-life of 3-5 months and accumulates and concentrates in the liver and adipose tissue after low-dose, repeated exposure. Repeated administration of octachlorodibenzo-p-dioxin causes increases in 7-ethoxyresorufin-O-deethylase (7-EROD) activity and total cytochrome P-450 levels[1].

• Target Antigen:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/octachlorodibenzo-p-dioxin.html

• Smiles:

  ClC1=C(Cl)C2=C(OC3=C(O2)C(Cl)=C(Cl)C(Cl)=C3Cl)C(Cl)=C1Cl

• Molecular Weight:

  459.75

• References & Citations:

  [1]Birnbaum LS, et al. Disposition of octachlorodibenzo-p-dioxin (OCDD) in male rats. Toxicol Appl Pharmacol. 1988 Mar 30;93(1):22-30.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3268-87-9