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MONNA

CAT: 0804-HY-100613-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100613-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MONNA is a potent transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with an IC50 of 80 nM. MONNA induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions[1].
CAS Number
1572936-83-4
UNSPSC
12352005
Target
Chloride Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/monna.html
Purity
99.87
Solubility
DMSO : 55.56 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC([N+]([O-])=O)=CC=C1NC2=CC(OC)=C3C=CC=CC3=C2
Molecular Formula
C18H14N2O5
Molecular Weight
338.31
References & Citations
[1]Oh SJ, et al. MONNA, a potent and selective blocker for transmembrane protein with unknown function 16/anoctamin-1. Mol Pharmacol. 2013 Nov;84 (5) :726-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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