Deferitazole

Deferitazole

• CAS Number: 945635-15-4
• UNSPSC Description: Deferitazole (FBS 0701) is an orally active iron chelator. Deferitazole shows antimalarial activity and Can be used for study of malaria [1][2].
• Target Antigen: Ferroptosis; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection;Apoptosis
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/deferitazole.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@]1(C)N=C(C2=CC=CC(OCCOCCOCCOC)=C2O)SC1)O
• Molecular Weight: 399.46
• References & Citations: [1]Hider RC, et al. Deferitazole, a new orally active iron chelator. Dalton Trans. 2015;44(11):5197-5204.|[2]Ferrer P, et al. Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model. PLoS One. 2012;7(5):e37171.
• Shipping Conditions: Room temperature
• Clinical Information: Phase 2