Deferitazole

• UNSPSC Description:

  Deferitazole (FBS 0701) is an orally active iron chelator. Deferitazole shows antimalarial activity and Can be used for study of malaria [1][2].

• Target Antigen:

  Ferroptosis; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/deferitazole.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@]1(C)N=C(C2=CC=CC(OCCOCCOCCOC)=C2O)SC1)O

• Molecular Weight:

  399.46

• References & Citations:

  [1]Hider RC, et al. Deferitazole, a new orally active iron chelator. Dalton Trans. 2015;44(11):5197-5204.|[2]Ferrer P, et al. Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model. PLoS One. 2012;7(5):e37171.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  945635-15-4