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Isocytosine

CAT: 0804-HY-W002272-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W002272-01Size:1 g
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Description
Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and used as a nucleobase of hachimoji RNA[1][2].
CAS Number
108-53-2
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Isocytosine.html
Concentration
10mM
Purity
99.71
Solubility
DMSO : 31.82 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N=C(N)NC=C1
Molecular Formula
C4H5N3O
Molecular Weight
111.10
Precautions
H302, H319
References & Citations
[1]"Isocytosine". Molecule of the Week. American Chemical Society. Retrieved November 1, 2012.|[2]Hoshika S, et al. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science. 2019 Feb 22;363 (6429) :884-887.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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