11-​Keto-​beta-​boswellic acid

11-​Keto-​beta-​boswellic acid

• CAS Number: 17019-92-0
• UNSPSC Description: 11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production[1].
• Target Antigen: Leukotriene Receptor; Lipoxygenase; NF-κB
• Type: Natural Products
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease;NF-κB
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/11-keto-beta-boswellic-acid.html
• Purity: 99.96
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: C[C@@]1([C@@]2(CC[C@]3(CC[C@H]([C@@H]([C@]3(C2=C4)[H])C)C)C)C)CC[C@@]5([H])[C@](C(O)=O)(C)[C@H](O)CC[C@]5(C)[C@@]1([H])C4=O
• Molecular Weight: 470.68
• References & Citations: [1]Miscioscia E, et al. Measurement of 3-acetyl-11-keto-beta-boswellic acid and 11-keto-beta-boswellic acid in Boswellia serrata Supplements Administered to Dogs. BMC Vet Res. 2019 Aug 1;15(1):270.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported