Carbutamide

• Description:

  Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity[1].

• Product Name Alternative:

  BZ-55

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/carbutamide.html

• Concentration:

  10mM

• Purity:

  99.43

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=S (C1=CC=C (N) C=C1) (NC (NCCCC) =O) =O

• Molecular Formula:

  C11H17N3O3S

• Molecular Weight:

  271.34

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Kleinsorge H, et al. Carbutamide--the first oral antidiabetic. A retrospect. Exp Clin Endocrinol Diabetes. 1998;106 (2) :149-51.|[2]ROOT MA, et al. Pharmacology of carbutamide (p-aminophenylsulfonyl butylcarbamide) . J Pharmacol Exp Ther. 1957 Apr;119 (4) :468-78.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  339-43-5