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Sulfamerazine

CAT: 0804-HY-B0512-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0512-01Size:500 mg
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Description
Sulfamerazine (RP-2632) is a sulfonamide antibacterial. Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes[1].
CAS Number
127-79-7
Product Name Alternative
RP2632
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sulfamerazine.html
Concentration
10mM
Purity
99.82
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
O=S(C1=CC=C(N)C=C1)(NC2=NC=CC(C)=N2)=O
Molecular Formula
C11H12N4O2S
Molecular Weight
264.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Aday B, et al. Synthesis of novel sulfonamide analogs containing sulfamerazine/sulfaguanidine and their biological activities. J Enzyme Inhib Med Chem. 2016 Dec;31 (6) :1005-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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