Calcineurin A α Isoform Human Recombinant

• Description:

  Calcineurin A α Isoform Human Recombinant _x000D_ Catalog number: B2016836_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 60.8 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Calmodulin-dependent Calcineurin A Subunit α Isoform, CALNA1, CAM-PRP Catalytic Subunit, CCN1, CNA1, PPP2B, PPP3CA, Protein Phosphatase 2B, Serine/threonine-Protein Phosphatase 2B Catalytic Subunit α Isoform_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Mizuguchi T, Nakashima M, Kato M, Okamoto N, Kurahashi H, Ekhilevitch N, Shiina M, Nishimura G, Shibata T, Matsuo M, Ikeda T, Ogata K, Tsuchida N, Mitsuhashi S, Miyatake S, Takata A, Miyake N, Hata K, Kaname T, Matsubara Y, Saitsu H, Matsumoto N. Loss-of-function and gain-of-function mutations in PPP3CA cause two distinct disorders Hum Mol Genet. 2018 Apr 15;27(8):1421-1433._x000D_ 2: Elliott WJ. Drug interactions and drugs that affect blood pressure J Clin Hypertens (Greenwich). 2006 Oct;8(10):731-7._x000D_ 3: Luo C, Burgeon E, Carew JA, McCaffrey PG, Badalian TM, Lane WS, Hogan PG, Rao A. Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes Mol Cell Biol. 1996 Jul;16(7):3955-66._x000D_ 4: Kilka S, Erdmann F, Migdoll A, Fischer G, Weiwad M. The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding Biochemistry. 2009 Mar 10;48(9):1900-10._x000D_ 5: Ammar YB, Takeda S, Hisamitsu T, Mori H, Wakabayashi S. Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation EMBO J. 2006 Jun 7;25(11):2315-25._x000D_ 6: de Frutos S, Nitta CH, Caldwell E, Friedman J, González Bosc LV. Regulation of soluble guanylyl cyclase-alpha1 expression in chronic hypoxia-induced pulmonary hypertension: role of NFATc3 and HuR Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L475-86._x000D_ 7: Cumbay MG, Watts VJ. Novel regulatory properties of human type 9 adenylate cyclase J Pharmacol Exp Ther. 2004 Jul;310(1):108-15._x000D_ 8: Ueki K, Kincaid RL. Interchangeable associations of calcineurin regulatory subunit isoforms with mammalian and fungal catalytic subunits J Biol Chem. 1993 Mar 25;268(9):6554-9._x000D_ 9: Qiao L, Hu J, Qiu X, Wang C, Peng J, Zhang C, Zhang M, Lu H, Chen W. LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles Autophagy. 2023 Nov;19(11):2837-2852._x000D_ 10: Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E, Piccolella M, Galbiati M, Garrè M, Morelli E, Vaccari T, Poletti A. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration Autophagy. 2019 Apr;15(4):631-651. _x000D_ _x000D_ Products Related to Calcineurin A α Isoform Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2016836 (50 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3