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Nafadotride

CAT: 0804-HY-110010-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-110010-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nafadotride is a dopamine D3 receptor antagonist. Nafadotrode regulates dopamine signaling primarily by antagonizing dopamine D3 receptors. The dopamine D3 receptor plays an important role in regulating emotion, motivation, reward, and certain motor functions. By blocking these receptors, Nafadotrode may affect neurotransmission processes associated with these functions. Nafadotrode can be used to explore the role of dopamine D3 receptors in various behavioral and neuropsychiatric disorders[1].
CAS Number
149649-22-9
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nafadotride.html
Purity
99.78
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C(C(NCC2N(CCC2)CCCC)=O)C=C(C#N)C3=CC=CC=C13
Molecular Formula
C22H27N3O2
Molecular Weight
365.47
References & Citations
[1]Banasikowski T J, et al. Reduced expression of haloperidol conditioned catalepsy in rats by the dopamine D3 receptor antagonists nafadotride and NGB 2904[J]. European Neuropsychopharmacology, 2012, 22 (10) : 761-768.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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