Bis-PEG13-NHS ester

• Description:

  Bis-PEG13-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG13-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bis-peg13-nhs-ester.html

• Purity:

  98.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)

• Smiles:

  O=C (ON1C (CCC1=O) =O) CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC (ON2C (CCC2=O) =O) =O

• Molecular Formula:

  C38H64N2O21

• Molecular Weight:

  884.92

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]John L. Magnani, et al. Highly potent multimeric e-selectin antagonists. WO2018068010A1

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; Cleavable Linker; PEG Linkers

• CAS Number:

  2221949-00-2