IGF1 Recombinant Rabbit Monoclonal Antibody [JE30-01]

IGF1 Recombinant Rabbit Monoclonal Antibody [JE30-01]

• Description: Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects in adults. In the 1950s IGF-1 was called "sulfation factor" because it stimulated sulfation of cartilage in vitro, and in the 1970s due to its effects it was termed "nonsuppressible insulin-like activity" (NSILA). IGF-1 is a protein that in humans is encoded by the IGF1 gene. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7,649 daltons. In dogs, an ancient mutation in IGF1 is the primary cause of the toy phenotype. IGF-1 is produced primarily by the liver. Production is stimulated by growth hormone (GH). Most of IGF-1 is bound to one of 6 binding proteins (IGF-BP). IGFBP-1 is regulated by insulin. IGF-1 is produced throughout life; the highest rates of IGF-1 production occur during the pubertal growth spurt. The lowest levels occur in infancy and old age. Low IGF-1 levels are associated with cardiovascular disease, while high GF-1 levels are associated with cancer. Mid-range IGF-1 levels are associated with the lowest mortality.
• Product Name Alternative: IBP1 antibody IGF I antibody IGF IA antibody IGF IB antibody IGF-I antibody Igf1 antibody IGF1_HUMAN antibody IGF1A antibody IGFI antibody IGFIA antibody Insulin like growth factor 1 (somatomedin C) antibody Insulin like growth factor 1 antibody Insulin like growth factor IA antibody Insulin like growth factor IB antibody Insulin-like growth factor I antibody Mechano growth factor antibody MGF antibody OTTHUMP00000195080 antibody OTTHUMP00000195081 antibody OTTHUMP00000195082 antibody OTTHUMP00000195083 antibody OTTHUMP00000195084 antibody Somatomedia C antibody Somatomedin C antibody Somatomedin-C antibody
• Abbreviation: IGF1, IBP1
• CAS Number: 9000-83-3
• Swiss Prot: P05019 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within
• Isotype: IgG
• Clone: JE30-01
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 22 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes