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Rhamnetin

CAT: 0804-HY-N7036-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7036-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2 and histone deacetylase 2 (HDAC2) . Rhamnetin exhibits antitumor, antioxidant and anti-inflammatory activity[1][2].
CAS Number
90-19-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; HDAC; Phospholipase
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rhamnetin.html
Purity
99.18
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC1=C(C2=CC=C(O)C(O)=C2)OC3=C(C(O)=CC(OC)=C3)C1=O
Molecular Formula
C16H12O7
Molecular Weight
316.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Novo Belchor M, et al. Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secretory Phospholipase A2. Molecules. 2017 Aug 31;22 (9) .|[2]Bharadwaj KK, et al., Rhamnetin, a nutraceutical flavonoid arrests cell cycle progression of human ovarian cancer (SKOV3) cells by inhibiting the histone deacetylase 2 protein. J Biomol Struct Dyn. 2024;42 (24) :13421-13436.|[3]Zhang W, et al., Rhamnetin attenuates cognitive deficit and inhibits hippocampal inflammatory response and oxidative stress in rats with traumatic brain injury. Cent Eur J Immunol. 2015;40 (1) :35-41.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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