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D-Cysteine

CAT: 0804-HY-W018555-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W018555-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day[1][2][3][4].
CAS Number
921-01-7
UNSPSC
12352211
Hazard Statement
H302
Target
Bacterial; Endogenous Metabolite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-cysteine.html
Purity
98.0
Solubility
H2O : 4 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N[C@H](CS)C(O)=O
Molecular Formula
C3H7NO2S
Molecular Weight
121.16
Precautions
H302
References & Citations
[1]Soutourina J, et al. Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine. J Biol Chem. 2001 Nov 2;276 (44) :40864-72.|[2]Guo X1, et al. Effect of D-cysteine on dual-species biofilms of Streptococcus mutans and Streptococcus sanguinis. Sci Rep. 2019 Apr 30;9 (1) :6689.|[3]Shibui Y, et al. Comparisons of l-cysteine and d-cysteine toxicity in 4-week repeated-dose toxicity studies of rats receiving daily oral administration. J Toxicol Pathol. 2017 Jul;30 (3) :217-229.|[4]Roychaudhuri R, et al. Mammalian D-cysteine: A novel regulator of neural progenitor cell proliferation Mammalian D-cysteine: A novel regulator of neural progenitor cell proliferation Endogenous D-cysteine, the stereoisomer with rapid spontaneous in vitro racemization rate, has major neural roles. Bioessays. 2022 Jul;44 (7) :e2200002.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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