Phomalactone

CAT: 0804-HY-N10269Size: 1 EachDry Ice: NoHazardous: No

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Description

Phomalactone, produced by the fungus Nigrospora sphaerica, specifically inhibits the mycelial growth of Phytophthora infestans, with an MIC value of 2.5 mg/L[1]. Phomalactone is phytotoxic to Z. elegans and other plant species by inhibition of seedling growth and by causing electrolyte leakage from photosynthetic tissues of both Z. elegans leaves and cucumber cotyledons[2].

CAS Number

28921-94-0

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Endogenous Metabolite; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/phomalactone.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C[C@H](O)[C@H](/C=C/C)O1

Molecular Formula

C8H10O3

Molecular Weight

154.16

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Kim JC, et al. Activity against plant pathogenic fungi of phomalactone isolated from Nigrospora sphaerica. Pest Manag Sci. 2001;57 (6) :554-559. |[2]Meepagala KM, et al. Phomalactone from a Phytopathogenic Fungus Infecting ZINNIA elegans (ASTERACEAE) Leaves. J Chem Ecol. 2015;41 (7) :602-612.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

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