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Icotinib (Standard)

CAT: 0804-HY-15164ARSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15164ARSize:1 Each
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Description
Icotinib (Standard) is the analytical standard of Icotinib. This product is intended for research and analytical applications. Icotinib (BPI-2009) is a potent and specific EGFR inhibitor with an IC50 of 5 nM; also inhibits mutant EGFRL858R, EGFRL858R/T790M, EGFRT790M and EGFRL861Q. Icotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
610798-31-7
Product Name Alternative
BPI-2009 (Standard)
UNSPSC
12352005
Target
EGFR; Reference Standards
Type
Reference Standards
Related Pathways
JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icotinib-standard.html
Smiles
C#CC1=CC(NC2=C(C=C(OCCOCCOCCO3)C3=C4)C4=NC=N2)=CC=C1
Molecular Formula
C22H21N3O4
Molecular Weight
391.42
References & Citations
[1]Tan F, et al. Icotinib (BPI-2009H), a novel EGFR tyrosine kinase inhibitor, displays potent efficacy in preclinical studies. Lung Cancer. 2012 May;76 (2) :177-82.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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