Products for Research Use Only
RegisterLogin

CBS-3595

CAT: 0804-HY-111164Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-111164Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CBS-3595 is a dual inhibitor of p38 MAP kinase and phosphodiesterase 4 with anti-inflammatory and anti-allodynic activities. CBS-3595 reduces the production of the proinflammatory cytokine IL-6 and increases the levels of the anti-inflammatory cytokine IL-10 in rats. CBS-3595 reduces paw oedema formation in the Complete Freund’s adjuvant (CFA) -induced arthritis rat model. CBS-3595 is promising for research of autoimmune diseases[1].
CAS Number
908380-97-2
UNSPSC
12352005
Target
P38 MAPK; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cbs-3595.html
Smiles
CC(NC1=NC=CC(C2=C(C3=CC=C(F)C=C3)N=C(S(C)=O)N2C)=C1)=O
Molecular Formula
C18H17FN4O2S
Molecular Weight
372.42
References & Citations
[1]Koch DA, et al. Efficacy and gastrointestinal tolerability of ML3403, a selective inhibitor of p38 MAP kinase and CBS-3595, a dual inhibitor of p38 MAP kinase and phosphodiesterase 4 in CFA-induced arthritis in rats. Rheumatology (Oxford) . 2014 Mar;53 (3) :425-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-R04437A-01Rno-miR-3595 agomir
HY-RI04437A-01Rno-miR-3595 antagomir
HY-RI04437-01Rno-miR-3595 inhibitor
HY-R04437-01Rno-miR-3595 mimic
HY-P5343P53 CBS
HY-177767EY-CBS
HY-105983A-01CBS-1114 (hydrochloride)
HY-P705450Cbs, Mouse (His)
HY-P72118-01CBS, Human (His)
HY-P82403-01CBS Antibody (YA2148, Rabbit)

Alternative Products

CatalogName
MBS5776687CBS-3595
MBS8297964-01rno-miR-3595 miRNA Inhibitor
CMR0670-01Rno-miR-3595 miRNA Mimic
MBS8321106-01rno-miR-3595 miRNA Antagomir
GTR19294714-01Rno-miR-3595 miRNA Agomir
mr0268AdmiRa-rno-mir-3595 Virus
309474-01CBS
abx890411-01Rat rno-miR-3595 miRNA Antagomir
abx885164-01Rat rno-miR-3595 miRNA Agomir
mr5440AdmiRa-rno-miR-3595-Off Virus

Popular Products