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Protein A

CAT: 0804-HY-NP006Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-NP006Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protein A (SPA) is an immunoglobulin (Ig) binding protein that exists on the surface of bacteria and can be freely secreted into the extracellular environment. Protein A blocks opsonization and phagocytosis and induces B-cell death in vitro by binding to the Fc region of antibodies and the Fab region of B-cell receptors. Protein A has the ability to inhibit opsonization and phagocytosis in vitro[1].
CAS Number
308083-69-4
Product Name Alternative
SPA
UNSPSC
12352200
Target
Endogenous Metabolite
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/protein-a.html
Purity
93.27
Solubility
10 mM in DMSO
Smiles
[ProteinA]
References & Citations
[1]Kobayashi SD, et al. Staphylococcus aureus protein A promotes immune suppression. mBio. 2013 Oct 1;4 (5) :e00764-13.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Biochemical Assay Reagents
Clinical Information
Phase 3