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Isovitexin

CAT: 0804-HY-N0773-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0773-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.
CAS Number
38953-85-4
Product Name Alternative
Saponaretin; Homovitexin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
JNK; NF-κB
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Isovitexin.html
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OC1=C(C2=O)C(OC(C3=CC=C(O)C=C3)=C2)=CC(O)=C1[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO
Molecular Formula
C21H20O10
Molecular Weight
432.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Lv H, et al. Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways. Int J Biol Sci. 2016 Jan 1;12 (1) :72-86.|[2]Hu JJ, et al. Isovitexin alleviates liver injury induced by lipopolysaccharide/d-galactosamine by activating Nrf2 and inhibiting NF-κB activation. Microb Pathog. 2018 Mar 29;119:86-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
JNK1; JNK2; NF-κB

Alternative Products

CatalogName
N2747-20Isovitexin

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