LDLR antibody

• Background:

  LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.

• Synonyms:

  Low-density lipoprotein receptor (LDL receptor) |LDLR

• Gene ID:

  3949

• UniProt:

  P01130

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Low density lipoprotein receptor

• Target:

  LDLR

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Cardiovascular, Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  100-160 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB

• Immunogen Sequence:

  455-607aa