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GW837016X

CAT: 0804-HY-129288Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129288Size:1 Each
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Description
GW837016X (NEU-391) is an orally active ErbB-2 kinase covalent inhibitor. GW837016X also is a potent antitrypanosome agent. GW837016X inhibits mitosis and cytokinesis[1].
CAS Number
833473-68-0
Product Name Alternative
NEU-391
UNSPSC
12352005
Target
EGFR; Mitosis; Paraptosis
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gw837016x.html
Smiles
FC1=CC(COC2=CC=C(NC3=C4C(C=C(C#C[C@H]5NCCC5)S4)=NC=N3)C=C2Cl)=CC=C1
Molecular Formula
C25H20ClFN4OS
Molecular Weight
478.97
References & Citations
[1]Woodring JL, et al. Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation. ACS Med Chem Lett. 2018 Sep 4;9 (10) :996-1001.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ErbB2/HER2

Alternative Products

CatalogName
T68611-01GW837016X

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