Soyasapogenol B

• Description :

  Soyasapogenol B is a component of soy that has oral activity. Soyasapogenol B promotes autophagy and apoptosis. Soyasapogenol B has anti-inflammatory, antioxidant and antitumor activities[1][2][3].

• CAS Number :

  [595-15-3]

• UNSPSC :

  12352211

• Target :

  Apoptosis; Autophagy

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Autophagy

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/soyasapogenol-b.html

• Purity :

  99.91

• Solubility :

  DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  C[C@]12[C@]3(C([C@@]4([H])[C@](C)([C@@H](CC(C)(C)C4)O)CC3)=CC[C@]1([H])[C@@]5([C@@]([C@](C)([C@@H](O)CC5)CO)([H])CC2)C)C

• Molecular Formula :

  C30H50O3

• Molecular Weight :

  458.72

• References & Citations :

  [1]Wang L, et al. Endoplasmic reticulum stress triggered by Soyasapogenol B promotes apoptosis and autophagy in colorectal cancer. Life Sci. 2019 Feb 1;218:16-24.|[2]Wang L, et al. Soyasapogenol B exhibits anti-growth and anti-metastatic activities in clear cell renal cell carcinoma. Naunyn Schmiedebergs Arch Pharmacol. 2019 May;392 (5) :551-563.|[3]Lee HJ, et al. Soyasapogenol B and Genistein Attenuate Lipopolysaccharide-Induced Memory Impairment in Mice by the Modulation of NF-κB-Mediated BDNF Expression. J Agric Food Chem. 2017 Aug 16;65 (32) :6877-6885.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported