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Sortilin Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334901-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334901-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR) .
Product Name Alternative
100 kDa NT receptor; Glycoprotein 95; Gp95; LDLCQ6; Neurotensin receptor 3; NT3; NTR3; SORT 1; Sortilin 1
UniProt
Q99523
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Sortilin
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q99523

Sortilin

SORT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99523
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SORT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DWI3, C0JYZ0, Q8IZ49
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembraneNucleus

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinLipoproteinPalmitatePhosphoprotein

Molecular function

Developmental proteinReceptor

Biological process

DifferentiationEndocytosisOsteogenesisProtein transportTransport

Domain

RepeatSignalTransmembraneTransmembrane helix

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