Bag3 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334885-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0013-GTR18334885-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.

Product Name Alternative

BAG 3; BAG family molecular chaperone regulator 3; Bag3; Bcl 2 binding protein; Bcl-2-binding protein Bis; BIS; CAIR 1; Docking protein CAIR 1; MFM6

UniProt

O95817

Reactivity

Human

Immunogen

A synthesized peptide derived from human Bag3

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Cell Biology

Purification

Affinity-chromatography

Dilution

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50

Form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IHC, IP, WB

Host or Source

Rabbit

Isotype

Rabbit IgG

UniProtKB · O95817

BAG family molecular chaperone regulator 3

BAG3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O95817
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: BAG3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: BAG-3
EC number: —
Processing: —
Secondary accessions: A8K5L8, Q3B763, Q9NT20, Q9P120

Protein keywords

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Biological process

Apoptosis

Disease

CardiomyopathyCharcot-Marie-Tooth diseaseDisease variantMyofibrillar myopathyNeurodegenerationNeuropathy

Molecular function

Chaperone

Cellular component

CytoplasmNucleus

Technical term

Proteomics identificationReference proteome

Domain

Repeat

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