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USP13 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334766-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334766-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.
Product Name Alternative
Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13
UniProt
Q92995
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human USP13
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:100
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q92995

Ubiquitin carboxyl-terminal hydrolase 13

UBP13_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92995
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
USP13
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.19.12
Processing
—
Secondary accessions
A8K2S3, B4DYF3, D3DNS2, Q96B25
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AutophagyUbl conjugation pathway

Cellular component

Cytoplasm

Molecular function

HydrolaseProteaseThiol protease

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Domain

RepeatZinc-finger

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APRab00260-01USP13 Rabbit Polyclonal Antibody
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