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WSTF Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334577-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334577-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph) . H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress.
Product Name Alternative
Baz1b; hWALP2; WALP2; WBRS9; WBSC10; WBSCR10; WBSCR9; WSTF
UniProt
Q9UIG0
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human WSTF
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 FC 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q9UIG0

Tyrosine-protein kinase BAZ1B

BAZ1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UIG0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BAZ1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.2
Processing
—
Secondary accessions
B9EGK3, D3DXE9, O95039, O95247, O95277, Q6P1K4, Q86UJ6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Domain

BromodomainCoiled coilZinc-finger

Biological process

DNA damageTranscriptionTranscription regulation

Molecular function

KinaseTransferaseTyrosine-protein kinase

Cellular component

Nucleus

Disease

Williams-Beuren syndrome

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