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PCAF Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334563-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334563-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A.
Product Name Alternative
CAF; GCN5; GCN5L; GCN5L1; KAT2B; P/CAF; p300/CBP??P300/CBP-associated factor??Lysine acetyltransferase 2B??PCAF
UniProt
Q92831
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human KAT2B / PCAF
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IP 1:50 FC 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q92831

Histone acetyltransferase KAT2B

KAT2B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92831
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KAT2B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.48
Processing
—
Secondary accessions
Q6NSK1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorAcyltransferaseTransferase

Biological process

Biological rhythmsCell cycleHost-virus interactionTranscriptionTranscription regulation

Domain

Bromodomain

Cellular component

CytoplasmCytoskeletonNucleus

Disease

Disease variant

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