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DDB1 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334935-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334935-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex) . The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.
Product Name Alternative
XPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1
UniProt
Q16531
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human DDB1
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB 1:10000~1:50000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q16531

DNA damage-binding protein 1

DDB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DDB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NG77, B2R648, B4DG00, O15176, Q13289, Q58F96
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsDNA damageDNA repairHost-virus interactionUbl conjugation pathway

Cellular component

CytoplasmNucleus

Disease

Disease variantIntellectual disability

Molecular function

DNA-binding

Domain

RepeatWD repeat

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