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ACTL6A Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334602-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334602-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix.
Product Name Alternative
ACTL6; ACTL6A; Arp4; ArpNbeta; BAF53; BAF53A; hArpN beta; INO80K
UniProt
O96019
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human ACTL6A
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · O96019

Actin-like protein 6A

ACL6A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O96019
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ACTL6A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KMN1, D3DNR9, Q8TAE5, Q9BVS8, Q9H0W6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorChromatin regulator

Coding sequence diversity

Alternative splicing

Disease

Disease variantIntellectual disability

Biological process

DNA damageDNA recombinationDNA repairGrowth regulationNeurogenesisTranscriptionTranscription regulation

Cellular component

Nucleus

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