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MTH1 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334448-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334448-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions.
Product Name Alternative
MTH1; NUDT 1
UniProt
P36639
Reactivity
Human
Immunogen
A synthesized peptide derived from human MTH1
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:100
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P36639

Oxidized purine nucleoside triphosphate hydrolase

8ODP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P36639
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NUDT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.1.56
Processing
—
Secondary accessions
A4D205, Q6LES7, Q6P0Y6, Q7Z7N6, Q8IV95, Q9UBM0, Q9UBM9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative initiation

Cellular component

CytoplasmMitochondrionNucleus

Molecular function

HydrolaseRNA-binding

Ligand

MagnesiumMetal-binding

Domain

Transit peptide

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