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PRMT7 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334218-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18334218-01Size:50 µL
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Description
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3) ; such methylation being required for the assembly and biogenesis of snRNP core particles.
Product Name Alternative
PRMT7; Protein arginine methyltransferase 7
UniProt
Q9NVM4
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human PRMT7
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q9NVM4

Protein arginine N-methyltransferase 7

ANM7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NVM4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRMT7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.321
Processing
—
Secondary accessions
B3KPR0, B3KUG9, B4E379, Q96PV5, Q9H9L0
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorMethyltransferaseTransferase

Cellular component

CytoplasmNucleus

Biological process

DifferentiationTranscriptionTranscription regulation

Disease

Disease variantDwarfismIntellectual disability

PTM

Methylation

Technical term

Proteomics identificationReference proteome

Domain

Repeat

Ligand

S-adenosyl-L-methionine

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