PPAR α (Phospho Ser21) rabbit pAb
CAT:
855-ES20158-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PPAR α (Phospho Ser21) rabbit pAb
- Description: Function: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. online information: Peroxisome proliferator-activated receptor entry, similarity: Belongs to the nuclear hormone receptor family. NR1 subfamily. similarity: Contains 1 nuclear receptor DNA-binding domain. subunit: Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13. tissue specificity: Skeletal muscle, liver, heart and kidney.
- Synonyms: Peroxisome proliferator-activated receptor alpha (PPAR-alpha;Nuclear receptor subfamily 1 group C member 1)
- Gene ID: 5465
- UniProt: Q07869
- Cellular Locus: Nucleus.
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: Synthesized peptide derived from human PPAR α (Phospho Ser21)
- Clonality: Polyclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000;IHC-p 1:50-300
- Molecular Weight: 52kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.