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A2B57

CAT: 0804-HY-117442Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117442Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A2B57 is a selective inhibitor for SIRT 2 with an IC50 of 6.3 µM[1].
CAS Number
1602733-73-2
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/a2b57.html
Smiles
O=C(C1=CC=CC=C1NC2=CC=C(C=C2)C3=CN(N=N3)CC4=CC=CC=C4)N
Molecular Formula
C22H19N5O
Molecular Weight
369.42
References & Citations
[1]Tatum PR, et al., Identification of novel SIRT2-selective inhibitors using a click chemistry approach. Bioorg Med Chem Lett. 2014 Apr 15;24 (8) :1871-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT2

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CatalogName
GTR19200631-01A2B57

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