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4'-Hydroxyvalerophenone

CAT: 0804-HY-W016604-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W016604-01Size:25 g
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Description
4'-Hydroxyvalerophenone (Compound 4) is an inhibitor of 17β-hydroxysteroid dehydrogenase (17β-HSD) with an IC50 of 60.52 μM[1].
CAS Number
2589-71-1
Product Name Alternative
4-Pentanoylphenol; 4-Valerylphenol
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-hydroxyvalerophenone.html
Purity
99.96
Solubility
10 mM in DMSO
Smiles
CCCCC(C1=CC=C(O)C=C1)=O
Molecular Formula
C11H14O2
Molecular Weight
178.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Lota RK, et al. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) . Bioorg Med Chem Lett. 2006 Sep 1;16 (17) :4519-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported