IL-2R beta/CD122, Canine (HEK293, Fc)

IL-2R beta/CD122, Canine (HEK293, Fc)

• UNSPSC Description: IL-2R beta (CD122), a type Ⅰ cytokine receptor expressed on T lymphocytes, is a receptor for IL-2 (Kd: 1 nM approximately)[1]. IL-2R beta mediates T cell immune responses, such as stimulating T cell proliferation and activating lymphokine-activated killer cells[2]. IL-2R beta/CD122 Protein, Canine (HEK293, Fc) is a recombinant canine IL-2R beta (M1-P244) with a C-Terminal hFc tag, which is produced in HEK293 cells.
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/il-2r-beta-cd122-protein-canine-hek293-fc.html
• Purity: 98.00
• Smiles: SVVNDTSKLT CFYNSKANIS CIWSWDGDLQ ATSCKIHAQP DRRPWNKSCE LLPMRPAFWA CYLILGSPDA QSLTSADVVG MSVMCHEGER WRILMTQDFK PFENLRLMAP NGLQVADVGT HKCNITWKVP QSSHYIKRYL EFEARKRSPG HSWEEASLMA LRQNQQWISL ETLTPDTLYE FQVRVRAQRG SHKTWSPWSQ PLAFRTRPAA RGKQSLPFP
• Molecular Weight: Approximately 68-75 kDa due to the glycosylation
• References & Citations: [1]Xiujuan Zhou, et al. Interleukin-2 (IL-2) Interacts With IL-2 Receptor Beta (IL-2Rβ): Its Potential to Enhance the Proliferation of CD4+ T Lymphocytes in Flounder ( Paralichthys olivaceus). Front Immunol. 2020 Sep 9;11:531790.|[2]R N Bamfordm, et al. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci U S A.1996 May|[3]Xiujuan Zhou, et al. Immunological characteristics of Interleukin-2 receptor subunit beta (IL-2Rβ) in flounder (Paralichtlys olivaceus): Implication for IL-2R function. Fish Shellfish Immunol. 2019 Oct;93:641-653.|[4]Akira Sakai, et al. The role of tumor-associated macrophages on serum soluble IL-2R levels in B-cell lymphomas. J Clin Exp Hematop. 2014;54(1):49-59.|[5]M Allouche, et al. Interleukin 2 receptors. Leuk Res. 1990;14(8):699-705.
• Shipping Conditions: Blue Ice
• Storage Conditions: Stored at -20°C for 2 years