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Andrographolide (Standard)

CAT: 0804-HY-N0191R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0191R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Andrographolide (Standard) is the analytical standard of Andrographolide. This product is intended for research and analytical applications. Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
CAS Number
5508-58-7
Product Name Alternative
Andrographis (Standard)
UNSPSC
12352005
Target
Autophagy; Influenza Virus; NF-κB; Parasite; Reference Standards; SARS-CoV
Type
Reference Standards
Related Pathways
Anti-infection; Autophagy; NF-κB; Others
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/andrographolide-standard.html
Purity
99.77
Smiles
O=C1OC[C@@H](O)/C1=C\C[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C
Molecular Formula
C20H30O5
Molecular Weight
350.45
References & Citations
[1]Zhai ZJ, et al. Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Br J Pharmacol. 2014 Feb;171 (3) :663-75.|[2]Gupta S, et al. Broad-spectrum antiviral properties of andrographolide. Arch Virol. 2017 Mar;162 (3) :611-623.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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