Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

• CAS Number: 1599440-20-6
• UNSPSC Description: Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1].
• Target Antigen: ADC Linker
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/gly-gly-phe-gly-nh-ch2-o-ch2cooh.html
• Purity: 99.98
• Solubility: DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : 100 mg/mL (ultrasonic)|DMSO : 3 mg/mL (ultrasonic;warming;heat to 80°C)
• Smiles: OC(COCNC(CNC([C@@H](NC(CNC(CN)=O)=O)CC1=CC=CC=C1)=O)=O)=O
• Molecular Weight: 423.42
• References & Citations: [1]Masuda,et al. Preparation of antibody-drug conjugates for cancer therapy. World Intellectual Property Organization, WO2014057687 A1. 2014-04-17.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, stored under nitrogen, away from moisture)
• Clinical Information: No Development Reported