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NPC1 Antibody (Center)

CAT: 0013-GTR18331128-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18331128-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Niemann-Pick C1 protein, NPC1
UniProt
O15118
Reactivity
Human
Immunogen
This NPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-620 amino acids from the Central region of human NPC1. Antigen Region: 591-620 aa.
Target
NPC1 (HGNC:7897)
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Metabolism Research, Neuroscience, Signal Transduction
Dilution
IF - 1:10-50, WB - 1:1000, IHC-P - 1:10-50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
142167 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
IF, IHC-P, WB
NCBI Accession Number
NP_000262.2
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · O15118

NPC intracellular cholesterol transporter 1

NPC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15118
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NPC1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DET3, Q9P130
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cholesterol metabolismHost-virus interactionLipid metabolismLipid transportSteroid metabolismSterol metabolismTransport

Disease

Disease variantNiemann-Pick disease

PTM

Disulfide bondGlycoprotein

Cellular component

EndosomeLysosomeMembrane

Molecular function

Host cell receptor for virus entryReceptor

Domain

SignalTransmembraneTransmembrane helix

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