8,11,14-Eicosatriynoic Acid

• Description:

  8,11,14-Eicosatriynoic Acid _x000D_ Catalog number: B2015008_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 mg_x000D_ Molecular Weight or Concentration: 300.4_x000D_ Supplied as: Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20° C_x000D_ Keywords: 8,11,14-ETI_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Lee KC, Chou KJ, Cheng JS, Wang JL, Tang KY, Tseng LL, Jan CR. Novel effects of 5,8,11-eicosatriynoic acid, a lipoxygenase inhibitor, on Ca2+ mobilization in Madin Darby canine kidney cells Pharmacol Toxicol. 2001 Jan;88(1):20-6._x000D_ 2: Hammarström S. Selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid Biochim Biophys Acta. 1977 Jun 22;487(3):517-9._x000D_ 3: Blomgren H, Hammarström S, Wasserman J. Synergistic enhancement of mitogen responses of human lymphocytes by inhibitors of cyclo-oxygenase and 5,8,11-eicosatriynoic acid, an inhibitor of 12-lipoxygenase and leukotriene biosynthesis Int Arch Allergy Appl Immunol. 1987;83(3):247-55._x000D_ 4: Takami M, Preston SL, Behrman HR. Eicosatetraynoic and eicosatriynoic acids, lipoxygenase inhibitors, block meiosis via antioxidant action Am J Physiol Cell Physiol. 2000 Apr;278(4):C646-50._x000D_ 5: Di Marzo V, De Petrocellis L, Gianfrani C, Cimino G. Biosynthesis, structure and biological activity of hydroxyeicosatetraenoic acids in Hydra vulgaris Biochem J. 1993 Oct 1;295 ( Pt 1)(Pt 1):23-9._x000D_ 6: Riehle M, Tsvetkov D, Gohlke BO, Preissner R, Harteneck C, Gollasch M, Nürnberg B. Molecular basis for the sensitivity of TRP channels to polyunsaturated fatty acids Naunyn Schmiedebergs Arch Pharmacol. 2018 Aug;391(8):833-846._x000D_ 7: DelliPizzi A, Guan H, Tong X, Takizawa H, Nasjletti A. Lipoxygenase-dependent mechanisms in hypertension Clin Exp Hypertens. 2000 Feb;22(2):181-92._x000D_ 8: Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls HR Jr, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids J Biol Chem. 2003 Mar 28;278(13):11303-11._x000D_ 9: Menon SD, Yap WH, Lim A, Tan YH. Arachidonic acid regulates the binding of human interferon in human skin fibroblasts Lipids. 1990 Jun;25(6):321-7._x000D_ 10: Nakao J, Ooyama T, Chang WC, Murota S, Orimo H. Platelets stimulate aortic smooth muscle cell migration in vitro. Involvement of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid Atherosclerosis. 1982 Jun;43(2-3):143-50. _x000D_ _x000D_ Products Related to 8,11,14-Eicosatriynoic Acid can be found at Chemicals

• Short Description:

  Catalog Number: B2015008 (1 mg)_x000D_ 8,11,14-Eicosatriynoic Acid is a high quality inhibitor of prostaglandin and leukotriene biosynthesis and arachidonic acid induced platelet aggregation. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5