APP Antibody

CAT: 0399-CSB-PA000875-02Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0399-CSB-PA000875-02Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Gene Aliases

A4 antibody; A4_HUMAN antibody; AAA antibody; ABETA antibody; ABPP antibody; AICD-50 antibody; AICD-57 antibody; AICD-59 antibody; AID (50) antibody; AID (57) antibody; AID (59) antibody; Alzheimer disease amyloid protein antibody; Amyloid intracellular domain 50 antibody; Amyloid intracellular domain 57 antibody; Amyloid intracellular domain 59 antibody; APP antibody; APPI antibody; Beta amyloid protein 42 antibody; Beta APP42 antibody; Beta-APP40 antibody; Beta-APP42 antibody; C31 antibody; Cerebral vascular amyloid peptide antibody; CVAP antibody; Gamma-CTF (50) antibody; Gamma-CTF (57) antibody; Gamma-CTF (59) antibody; PN-II antibody; PreA4 antibody; Protease nexin-II antibody; S-APP-alpha antibody; S-APP-beta antibody

UniProt

P05067

Host

Rabbit

Antigen Species

Human

Reactivity

Human, Mouse, Rat

Target Antigen

Synthesized peptide derived from Human Amyloid-β around the non-phosphorylation site of T743.

Target

APP

Clonality

Polyclonal

Conjugation

Non-conjugated

Field of Research

Neuroscience

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Conditions

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Type

Polyclonal Antibody

Tested Applications

WB, IHC, IF, ELISA; WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:40000

Isotype

IgG

UniProtKB · P05067

Amyloid-beta precursor protein

A4_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P05067
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: APP
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: APP
EC number: —
Processing: Precursor
Secondary accessions: B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q6GSC0, Q8WZ99, Q9BT38, Q9UC33, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

AmyloidCell membraneCell projectionCoated pitCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Biological process

ApoptosisCell adhesionEndocytosisNotch signaling pathway

Ligand

CopperIronMetal-bindingZinc

PTM

Disulfide bondGlycoproteinIsopeptide bondOxidationPhosphoproteinProteoglycanSulfationUbl conjugation

Molecular function

Heparin-bindingProtease inhibitorSerine protease inhibitor

Domain

SignalTransmembraneTransmembrane helix

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CSB-CL001950HU	APP
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CSB-EP001950MOc7-01	Recombinant Mouse Amyloid beta A4 protein (App)

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