EGFR Antibody (N-term)

CAT: 0013-GTR18329637-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0013-GTR18329637-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Product Name Alternative

Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1

UniProt

P00533

Reactivity

Human

Immunogen

This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR. Antigen Region: 259-287 aa.

Target

EGFR (HGNC:3236)

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cell Biology

Dilution

WB - 1:1000, IHC-P - 1:25

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Molecular Weight

134277 Da

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles

Notes

For research use only.

Prediction Reactivity

Mouse

Tested Applications

IHC-P, WB

NCBI Accession Number

NP_005219.2, NP_958441.1, NP_958439.1, NP_958440.1

Host or Source

Rabbit

Isotype

Rabbit IgG

UniProtKB · P00533

Epidermal growth factor receptor

EGFR_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P00533
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EGFR
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.7.10.1
Processing: Precursor
Secondary accessions: O00688, O00732, P06268, Q14225, Q68GS5, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Molecular function

Developmental proteinHost cell receptor for virus entryKinaseReceptorTransferaseTyrosine-protein kinase

Disease

Disease variantProto-oncogene

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Biological process

Host-virus interaction

Domain

RepeatSignalTransmembraneTransmembrane helix

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