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PARP1 Antibody (N-term)

CAT: 0013-GTR18329636-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18329636-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD (+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, PARP1, ADPRT, PPOL
UniProt
P09874
Reactivity
Human
Immunogen
This PARP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the N-terminal region of human PARP1. Antigen Region: 123-151 aa.
Target
PARP1 {ECO:0000303|PubMed:21680843, ECO:0000312|HGNC:HGNC:270}
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Dilution
WB - 1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
113084 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Mouse
Tested Applications
WB
NCBI Accession Number
NP_001609.2
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P09874

Poly [ADP-ribose] polymerase 1

PARP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09874
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PARP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PARP-1
EC number
2.4.2.30
Processing
—
Secondary accessions
B1ANJ4, Q8IUZ9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

Allosteric enzymeDNA-bindingGlycosyltransferaseNucleotidyltransferaseTransferase

Biological process

ApoptosisDNA damageDNA repairImmunityInnate immunityTranscriptionTranscription regulation

Cellular component

ChromosomeCytoplasmNucleus

Ligand

Metal-bindingNADZinc

Domain

RepeatZinc-finger

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