Anti-Cytokeratin 18 (KRT18)(rKRT18/1190)

• Description:

  This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  Cell Proliferation-inducing Gene 46 Protein; CK18; CYK18Cytokeratin Endo B; K18; Keratin-18; Kerd; KRT18

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  KRT18

• Gene ID:

  3875

• NCBI Gene ID:

  406013

• UniProt:

  P05783

• Cellular Locus:

  Cytoskeleton

• Host:

  Mouse

• Species Reactivity:

  Cat, Cow, Dog, Ferret, Goat, Hamster, Horse, Human, Marmoset, Mouse, Pig, Rat, Sheep

• Immunogen:

  Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431

• Target Antigen:

  Cytokeratin 18

• Clonality:

  Recombinant Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  rKRT18/1190

• Conjugation:

  Purified, BSA-free

• Disease:

  Tumor

• Source:

  Animal

• Applications:

  IHC, FFPE (verified) | WB (verified)

• Validated Applications:

  IHC, FFPE, WB

• Field of Research:

  Cancer, Cytoskeleton

• Positive Control:

  MCF-7 or HeLa cells (FACS/IF). Human breast carcinoma tissue (IHC).

• Concentration:

  1 mg/mL

• Buffer:

  PBS, no BSA, no azide

• Molecular Weight:

  45 kDa

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  -35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4