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CD74 (B-Cell Marker)

CAT: 0544-MBS4381446-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381446-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CD74]
NCBI Gene ID
972
Reactivity
Human, Baboon, Mouse
Does not react with Rat.
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
It recognizes a protein of ~35kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
Other Gene Names
[CD74; II; p33; DHLAG; HLADG; Ia-GAMMA]
Short Name
[CD74]
Other Product Names
[HLA class II histocompatibility antigen gamma chain; CD74 molecule]
Uniprot Accession Number
P044233

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M01340-1Anti-CD74 (B-Cell Marker) Monoclonal Antibody
36-1973-100Monoclonal Antibody to CD74 (B-Cell Marker) (Clone : SPM523)
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RA0065-C.1CD74 (B-Cell Marker) ; Clone LN-2 (Concentrate)
RA0066-C.5CD74 (B-Cell Marker) ; Clone CLIP/813 (Concentrate)
BNUM3127-50CD74 (B-Cell Marker) (CLIP/3127R), 1mg/mL
BNUB3127-100CD74 (B-Cell Marker) (CLIP/3127R), 0.2mg/mL
36-1975-100Monoclonal Antibody to CD74 (B-Cell Marker) (Clone : CLIP/813)
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